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Treating Physical Pain in Bipolar – Neuropathic Pain

Physical pain in bipolar, neuropathic pain, is difficult - but not impossible - to treat. Here are some options for treating physical, bipolar pain. Look here.

Physical pain in bipolar disorder is one of the hardest bipolar symptoms to treat (and, of course, not everyone experiences this). The physical pain in bipolar disorder is known as neuropathic pain. Neuropathic pain is commonly associated with spinal cord injuries or amputation but can occur in psychiatric disorders and in other illnesses as well. This neuropathic pain, physical pain in bipolar disorder, can be debilitating but there are options for treatment.

Physical Pain, Neuropathic Pain, in Bipolar Disorder

Yesterday, I was at my psychiatrist’s appointment and I was complaining about an all-over pain that I have that has no cause. It occurs every day and sometimes is so bad that moving makes me want to cry. (Not to mention the fact that even water from a shower is painful.)

He called this “pain syndrome.” And yes, that’s sure what it feels like to me. It feels like a syndrome defined by pain, pain, pain and pretty much nothing else.

He readily admitted that neuropathic pain in bipolar disorder (typically bipolar depression) is very difficult to treat. If you’re in remission, it may go away, but I am not that lucky. I was, honestly, expecting him to say that nothing could be done. I’ve had this pain for so long that I just assumed I must always have it. Surprisingly, this is not what he said.

Treatment of Neuropathic Pain

Physical pain in bipolar, neuropathic pain, is difficult - but not impossible - to treat. Here are some options for treating physical, bipolar pain. Look here.The treatment of neuropathic pain in bipolar disorder hasn’t really been studied, maybe because it’s rare or maybe because it’s unrecognized, I don’t know. But treating neuropathic pain in other conditions has been studied.

According to this Medscape article, the first-line medication treatments for neuropathic pain are:

  • Tricyclic antidepressants – these are the older antidepressants like amitriptyline (Elavil). Antidepressants are, obviously, a good choice for someone experiencing neuropathic pain due to depression but may not be suitable for someone with bipolar disorder due to the possibility of mixed mood or mania/hypomania induction.
  • Other antidepressants with evidence in treating neuropathic pain include venlafaxine (Effexor) and duloxetine (Cymbalta). Duloxetine actually has Food and Drug Administration (FDA) approved indications for treating several pain disorders. Again, these may not be appropriate for a person with bipolar disorder.
  • Gabapentin (Neurontin) – this is an anticonvulsant that is not typically used to treat bipolar disorder but may be; and like other anticonvulsants, it may be mood stabilizing and gabapentin is not known to cause mixed moods or hypomania/mania.
  • Pregabalin (Lyrica) – this is another anticonvulsant which has the advantages stated above but is prohibitively expensive for many. Pregabalin also has FDA approved indications for pain disorders.
  • Topical lidocaine (Lidopen) – this is an antidysrhythmic (used to treat heart rhythm irregularities) that is expensive and treats only localized pain.
  • Opioid analgesics – these are the pain drugs like morphine, oxycodone (OxyContin) and tramadol (Ultram) which can be used but have limited supporting evidence and are, obviously, rife for misuse and addiction. These are not a good choice for anyone with a background of addiction, obviously.

Combinations of medications can also be used to treat neuropathic pain due to, as this study on drug combinations states,

The most commonly studied drug classes in the context of neuropathic pain-antidepressants, anticonvulsants, and opioids-have only limited efficacy and frequent dose-limiting adverse effects . . .

So even if the above fails for you, a combination of medications may be effective.

The Good and the Bad of Treating Physical, Bipolar Pain

There is good news and bad news about treating physical, bipolar pain. The bad news is that treatment isn’t terribly successful for many (but people with bipolar disorder are used to this thanks to all the other medications that only work for some or partway).

The good news is that physical, bipolar pain can be treated and that a drug like gabapentin (suitable for many with bipolar disorder) may work to treat neuropathic pain in bipolar disorder. Like I said, this hasn’t been studied, but if you’re suffering from debilitating, physical pain associated with bipolar disorder, it’s still good news. It’s good news that just because we have a psychiatric illness doesn’t mean we have to live in physical pain (along with psychiatric pain) forever.

And don’t assume (like I did) that a doctor can’t help you with a bipolar symptom that seems impossible to treat. Talk to him or her about it anyway as he or she may surprise you.

Of course, I’m not a doctor so you should always take a look at the source (linked above) and discuss anything that interests you with your doctor. Because remember, drugs are only indicated for some people some of the time but, luckily, there are many options so there will likely be one to suit you (to at least try, anyway).

You can find Natasha Tracy on Facebook or Google+ or @Natasha_Tracy on Twitter or at Bipolar Burble, her blog.

Image of the brain by Allan Ajifo [CC BY 2.0], via Wikimedia Commons.

Author: Natasha Tracy

Natasha Tracy is a renowned speaker, award-winning advocate and author of Lost Marbles: Insights into My Life with Depression & Bipolar.

Find Natasha Tracy on her blog, Bipolar Burble, Twitter, Google+ and Facebook.

9 thoughts on “Treating Physical Pain in Bipolar – Neuropathic Pain”

  1. How is fibromyalgia pain related to Bipolar pain? My wife has been diagnosed with fibromyalgia for years, but I am certain she is bipolar. Her pains are severe and inexplicable and everywhere. We have been married 55 years and had a beautiful life together living out of the country for 20 years having adventures.. I find that sometimes just talking and messaging her comely I can ease some of the pain. She cries everyday and is chronically depressed. When she has a good day, it is so beautiful as she is a really special person.

    1. Hi Ron,

      I believe there is a relationship between fibromyalgia and bipolar, but this doesn’t necessarily mean your wife has bipolar. Pain, itself, can certainly make a person depressed (and just depression isn’t bipolar). The best thing to do is to see a doctor and get a formal diagnosis, if necessary.

      – Natasha Tracy

  2. Im desperate. Im in excruciating pain and have real diagnosed physical problems with joints all over but doesn’t explain the pain i am experiencing in just about every atom of my wretched body. Ive gone from a muscular size 10 -12 to a size 6 in a couple of months. I am not getting anywhere with Dr’s to the point where I can’t face another appointment with one ever again. Im also medication sensitive, so the steroids the gp prescribed followed by the opiods then amatriptaline caused major hypermania episodes with all the associated problems. They promptly stopped all treatment saying medicine doesn’t have all the answers. Im now £8000 in debt, unable to work and then my little girl of 9yrs old died in my arms and my life has fallen apart. I want to die so badly but a coward for one and have my 2 boys to try to look after on my own. Professionals have given up on me and so have I.

    1. Hi Em,

      I’m so sorry to hear about your issues with pain. I know what that’s like and I know how horrible it is.

      Please know that just because one doctor gave up on your doesn’t mean that all of them will. I have had doctors give up on me, only to find another and get well. Please don’t give up. Life doesn’t have to be this way. Reach out to another doctor — maybe a specialist. I know you don’t want to, but that is the path to feeling better.

      – Natasha Tracy

  3. I have peripheral neuropathy and always thought it was from my diabetes. I am bipolar and it really flared up after a long period of debilitating depression.

  4. I could not agree more. I am a 59 year old with a long history of Bipolar and get pain and fatigue usually accompanying the depressions but sometimes preceding them. All over the body, joints,limbs etc. Nothing shows up on blood tests etc. A mystery to my General Practitioner(physician). But rather the physical symptoms of bipolar depression. I have always had a severe course.
    I take over the counter medicines such as paracetamol & exercise (even though it is the last thing I want to do) seems to help.
    Thank you for identifying the physical pain as Bipolar is often mistakenly seen only as a mental illness.

  5. i have bi-polar disorder even though right now it seems that I AM bi-polar. I have always been a spectator of life, feeling like a monster, shattered, broken, and now, in a lot of neuropathic pain. I was prescribed gabapentin. I think it makes me cry.

  6. My first bipolar symptom, even before the depression, was chronic, debilitating, physical pain. I was told I was experiencing a somatic disorder of types because it was idiopathic, I was in my very early twenties. I was about to give up when my doctor got my to try Lyrica (now I use the generic) and it helped so much. Unfortunately not enough though. I was sent to a pain specialist who ended putting me on buprenorphine patch eventually, but she got me sectioned after I told her Tramadol was making me suicidal. Then I got my bipolar diagnosis, and got put on Depakote and Nabilone. So now I’m on Lyrica (for pain- also an anticonvulsant) Depakote (anticonvulsant for mood stabilizing) BuTrans (semi synthetic opioid for pain and mood) and Nabilone (synthetic cannabinoid for pain, mood, and to stimulate hunger). So far this combination has done wonders for me, but it took me years to get this far. I still have my bad days, the flare ups where I end up losing all the spoons I collected on my good days (check out ‘spoon theory’).

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