Avandaryl Type 2 Diabetes Treatment - Patient Information

Brand Names: Avandaryl
Generic Name: Rosiglitazone Maleate and Glimepride

Avandaryl (rosiglitazone maleate and glimepride) Full Prescribing Information

Why is Avandaryl prescribed?

Avandaryl is used for treatment of type 2 diabetes, by controlling blood sugar levels. Type 2 diabetes occurs when there is a build-up of sugar in the blood, which may lead to serious health conditions.

Most important fact about Avandaryl

Full diabetic therapy should include diet and weight management, through proper eating habits and exercise, for complete management.

How should you take Avandaryl?

Take the recommended dose orally, with your first meal of the day.

  • If you miss a dose...
    If you miss a dose of Avandaryl, take it as soon as you remember. If it is already time for your next dose, do not take double.
  • Storage instructions...
    Avandaryl should be stored in its original container at room temperature.

What side effects may occur?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Avandaryl.

  • Side effects may include:
    Abnormal ovulation, heart problems, liver or kidney problems, low or high blood sugar, swelling, weight gain

Why should Avandaryl not be prescribed?

Do not take Avandaryl if you are allergic/have had an allergic reaction to any of its ingredients. This medication is not recommended for children under the age of 18.

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Special warnings about Avandaryl

Inform your doctor if you get sick, injured, or have surgery while on Avandaryl. This drug may not properly control your blood sugar levels during these times.

Talk to your doctor about all of your medical conditions, especially if you have heart, liver or kidney problems, or are menopausal. Also, keep your doctor informed of all prescription, over-the-counter and herbal medicines you are taking.

Possible food and drug interactions when taking Avandaryl

If Avandaryl is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Avandaryl with the following:

Miconazole (oral)
Nicotinic acid sympathomimetics
Oral contraceptives
Other oral hypoglycemic agents
Thyroid products

Special information if you are pregnant or breastfeeding

Avandaryl should not be used during pregnancy; it is recommended to have a stable blood sugar level during pregnancy, therefore, talk with your doctor about beginning insulin therapy if you are pregnant or planning to become pregnant.

Recommended dosage for Avandaryl


The usual starting dose of Avandaryl is 4 milligrams (mg)/1 mg or 4 mg/2 mg once daily.


Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.

Last Updated: 11/09

Avandaryl (rosiglitazone maleate and glimepride) Full Prescribing Information

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APA Reference
Staff, H. (2009, November 2). Avandaryl Type 2 Diabetes Treatment - Patient Information, HealthyPlace. Retrieved on 2024, July 13 from

Last Updated: July 18, 2014

Medically reviewed by Harry Croft, MD

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