For depression patients who don't get relief with antidepressant medications alone, adding antipsychotic medications, like Seroquel or Abilify, may help. HealthyPlace.com Medical Director, Dr. Harry Croft, says for patients with tough-to-treat depression, this may provide significant relief. For comprehensive information on depression, visit the HealthyPlace.com Depression Information Center: http://www.healthyplace.com/depression/menu-id-68/