Chapter 5. Adverse Effects - Prolonged Seizures
5.1.2. Prolonged Seizures
Each facility should have policies outlining the steps to be taken to terminate prolonged seizures and status epilepticus (see Section 11.9.4).
5.1.3 Prolonged Apnea
Resources for maintaining an airway for an extended period, including intubation, should be available in the treatment room (see Chapters 9 and 10).
Systemic Side Effects
Headache and nausea are the most common systemic side effects of ECT. Systemic side effects should be identified and symptomatic treatment considered.
5.3 Treatment Emergent Mania
Instances in which patients switch from depressive or affectively mixed states into hypomania or mania during a course of ECT should be identified, and a determination to continue or suspend further treatment with ECT.
a) Orientation and memory function should be assessed prior to ECT and periodically throughout the ECT course to detect and monitor the presence of ECT-related cognitive dysfunction (see Section 12.2.1 for details). This assessment should attend to patient self-reports of memory difficulty.
b) Based on the assessment of the severity of cognitive side effects, the physician administering ECT should take appropriate action. The contributions of medications, ECT technique, and spacing of treatments should be reviewed. Potential treatment modifications include changing from bilateral to right unilateral electrode placement, decreasing the intensity of electrical stimulation, increasing the time interval between treatments, and/or altering the dosage of medications, or, if necessary, terminating the treatment course.
Table 1. Treatment factors that may increase or decrease the severity of adverse cognitive side effects
| Treatment factor | Associated with increased cognitive side effects | Steps to be taken to reduce cognitive side effects |
| Stimulus waveform | Sine wave | Change to brief pulse |
| Electrode placement | Bilateral | Change to right unilateral |
| Stimulus intensity | Grossly suprathreshold | Decrease electrical dose |
| Spacing of treatments | ECT administered 3-5 times per week | Decrease frequency or stop ECT |
| Number of seizures per session | Multiple (two ore more) seizures per session | Change to conventional ECT |
| Concomitant psychotropic medications | Lithium, benzodiazepines, neuroleptics, antidepressants | Reduce dose or stop psychotropics |
| Anesthetic medications | High dose may contribute to amnesia | Reduce dose as appropriate for light level of anesthesia |
next: Chapter 6. Pre-ECT Evaluation
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reviewed by:
Harry Croft, MD (Psychiatrist)
Medical Director, HealthyPlace.com
Created on February 14, 2007 Last Updated on January 12, 2012
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