When should the symptom-induced guilt and shame end and responsibility in mental illness begin? Chris T. (actual person, name changed) has been diagnosed with bipolar disorder. One of the ways his bipolar manifests is hypersexuality. This symptom drives Chris to act out sexually. He’s a married man and over the years has had two extramarital relationships. He has come perilously close on more than one occasion to losing his entire family. Chris feels guilt and shame. He doesn’t deny responsibility in his mental illness, but his wife is torn apart because of his actions.