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Medline Research on the Borderline Personality Disorder
Written by Dr. Leland Heller   
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May 03, 2007 A +  A -  RESET  

J Pers Assess 1986 Winter;50(4):540-53
"The MMPI, prototypal topology and borderline personality disorder"
Unstructured interviews were more reliable than the MMPI.

Percept Mot Skills 1986 Apr;62(2):579-85
"On the consistency of the MMPI in borderline personality disorder"
14 patients showed consistent results, but variability between patients. "A note of caution is advised for those investigators who assume that a prototypical borderline MMPI profile exists" (note: I had a patient who had a mildly abnormal MMPI when doing well, and the next day when dysphoric had one interpreted as 'strong antisocial features')"

J Clin Psychopharmacol 1986 Aug;6(4):236-9
"Development of melancholia during carbamazepine treatment in borderline personality disorder"
During carbamazepine (Tegretol) treatment 18% developed melancholia, which went away on discontinuation of carbamazepine. (Note: in my experience many of my patients with this pattern developed low thyroid - hypothyroidism - and the depression remitted with the addition of thyroid replacement hormone)

Acta Psychiatr Scand 1986 May;73(5):500-5
"Characterizing paranoia in the DSM-III borderline personality disorder"
"Paranoia was both more prevalent and severe in borderline patients."

J Clin Psychiatry 1987 May;48(5):181-4
"Is bulimia associated with borderline personality disorder? A controlled study"
Only 1.9% of bulimic patients in this study using the DIB instead of DSM criteria had the BPD. (The DIB in a previous study was felt to be relatively inaccurate in diagnosing the BPD)

Am J Psychiatry 1987 Jun;144(6);748-52
"Sexual practices among patients borderline personality disorder"
"Homosexuality was 10 times more common among the men and six times more common among the women and borderline personality disorder than in the general population or in a depressed control group." Bisexuality and paraphilias were also relatively common.

Arch Gen Psychiatry 1987 Jul;44(7):645-50
Auditory P300 in borderline personality disorder and schizophrenia
Those with BPD had different results on EEG, particularly in the P300 location, sharing a dysfunction of auditory neurointegration with schizophrenia.

Psychiatry Res 1987 Aug;21(4):307-11
"Lack of effect of dopamine receptor blockade on the TSH response to TRH in borderline personality disorder"
The reduction in TSH response to TRH is not due to dopamine function.

J Clin Psychiatry 1987 Aug;48 Suppl:15-25
"Psychopharmacology of borderline personality disorder: a review"
"The frequent presence of comorbid disorders and the occurrence of a wide array of possible target symptoms complicate clinical assessment. "Neuroleptics, MAO inhibitors and carbamazepine (Tegretol) were helpful.

Am J Psychiatry 1988 Jun;145(6):737-9
"Suicide attempts in patients with borderline personality disorder"
BPD patients with both depression and substance abuse are at a higher risk of suicide.

Am J Psychiatry 1988 Jul;145(7):809-14
"The amphetamine challenge test in patients with borderline disorder"
Amphetamine administration helped those with BPD unless they also had the schizotypal personality disorder. (How much of the effect was on borderlines who had attention deficit disorder wasn't addressed)

Can J Psychiatry 1988 Jun;33(5):336-40
"Characteristics of borderline personality disorder: A Canadian study"
Inpatients with the BPD have a chronic severe disorder, which begins in adolescence and probably were neglected or abused as children.

Am J Psychiatry 1988 Nov;145(11):1453-4
"A comparison of three measures for the diagnosis of borderline personality disorder"
Three testing systems showed were not good for making the diagnosis, and more than half those studied had at least three personality disorder diagnoses.


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Last Updated( Feb 04, 2009 )
reviewed by: Harry Croft, MD
Psychiatrist, HealthyPlace.com Medical Director
 

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