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Cylert (Pemoline)
Patient Information
Pronounced: SIGH-lert
Generic name: Pemoline
Why is Cylert prescribed?
Cylert is used to help treat children who have attention deficit disorder
with hyperactivity. However, this condition does not always require drug
treatment. Drugs such as Cylert should be taken as part of a comprehensive
treatment plan offering psychological and educational support to help the
child become more stable.
Children who have attention deficit disorder with hyperactivity may show
signs of:
Emotional mood swings Hyperactivity Impulsive actions Moderate to severe
distractibility Short attention span
Most important fact about Cylert
Cylert has been known to cause rare cases of liver damage, some serious
enough to be fatal. Children taking Cylert should have their liver function
tested every 2 weeks. If the child develops any signs of liver damage, call
your doctor immediately. Warning signs include fatigue, loss of appetite,
digestive problems, yellow skin or eyes, and pain in the upper right section
of the abdomen.
How should you take Cylert?
Cylert should be taken once a day, in the morning.
---If you miss a dose...
Have your child take it as soon as you remember, then go back to the
regular schedule. If you do not remember it until the next day, skip the
missed dose and go back to the regular schedule. Do not give 2 doses at
once.
---Storage instructions...
Store at room temperature.
What side effects may occur when taking Cylert?
Side effects cannot be anticipated. If any develop or change in
intensity, inform your doctor as soon as possible. Only your doctor can
determine if it is safe for your child to continue taking Cylert.
-
The most common Cylert side effects may include:
Insomnia
-
Less common side effects may include:
Depression, dizziness, drowsiness, hallucinations, headache, hepatitis
and other liver problems, increased irritability, involuntary,
fragmented movements of the face, eyes, lips, tongue, arms, and legs,
loss of appetite, mild depression, nausea, seizures, skin rash,
stomachache, suppressed growth, uncontrolled vocal outbursts (such as
grunts, shouts, and obscene language), weight loss, yellowing of skin or
eyes
-
Rare side effects may include: A
rare form of anemia with symptoms such as bleeding gums, bruising, chest
pain, fatigue, headache, nosebleeds, and abnormal paleness
Why should Cylert not be prescribed?
Your child should not be using Cylert if he or she is allergic to it or
if he or she has liver problems.
Special warnings about Cylert
Cylert may cause dizziness. Warn your child to be careful climbing stairs
or participating in activities that require mental alertness.
Although there have been no reports that Cylert is physically addictive,
it is chemically similar to a class of drugs that are potentially addictive.
Make sure your child takes no more than the prescribed dosage.
Children who take this drug on a long-term basis should be carefully
monitored for signs of stunted growth.
Your doctor will be extra cautious if your child has kidney problems.
Children who have a psychiatric illness who take Cylert may experience
increasingly disordered thoughts and behavioral disturbances.
Possible food and drug interactions when taking Cylert
If Cylert is taken with certain other drugs, the effects of either could
be increased, decreased, or altered. It is especially important to check
with your doctor before combining Cylert with the following:
Seizure medications such as Tegretol Other drugs that affect the central
nervous system (brain and spinal cord) such as Ritalin
Special information if you are pregnant or breastfeeding
This drug is for use only in children, and its effects in pregnancy have
not been adequately studied. Cylert should be used during pregnancy only if
it is clearly necessary. The drug may appear in breast milk and affect the
baby.
Recommended dosage for Cylert
The recommended beginning dose is 37.5 milligrams daily. Dosages may be
gradually increased if needed. Most children take doses ranging from 56.25
to 75 milligrams a day. The maximum recommended daily dose of Cylert is
112.5 milligrams. Significant improvement is gradual and may not be apparent
until the third or fourth week of treatment with Cylert.
Your doctor may occasionally stop treatment with Cylert to see whether
behavioral problems return and whether further treatment with Cylert is
necessary.
Overdosage of Cylert
Any medication taken in excess can have serious consequences. If you
suspect an overdose, seek medical help immediately.
- Symptoms of Cylert overdose may include: Agitation, coma,
confusion, convulsions, delirium, dilated pupils, exaggerated feeling of
well-being, extremely high temperature, flushing, hallucinations,
headache, high blood pressure, increased heart rate, increased reflex
reactions, muscle twitches, sweating, tremors, vomiting
Full Cylert Prescribing Information
Last updated: 12/2005
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