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Desoxyn (Methamphetamine)
Patient Information
Pronounced: des-OK-sin
Generic name: Methamphetamine hydrochloride
Why is Desoxyn prescribed?
Desoxyn is used to treat Attention Deficit Hyperactivity Disorder (ADHD).
This drug is given as part of a total treatment program that includes
psychological, educational, and social measures. Symptoms of ADHD include
continual problems with moderate to severe distractibility, short attention
span, hyperactivity, emotional instability, and impulsiveness.
Desoxyn also may be used for a short time as part of an overall diet plan
for weight reduction. Desoxyn is given only when other weight loss drugs and
weight loss programs have been unsuccessful.
Most important fact about Desoxyn
Excessive doses of this medication can produce addiction. Individuals who
stop taking this medication after taking high doses for a long time may
suffer withdrawal symptoms, including extreme tiredness, depression, and
sleep disorders. Signs of excessive use of Desoxyn include severe skin
inflammation, difficulty sleeping, irritability, hyperactivity, personality
changes, and psychiatric problems.
Desoxyn can lose its effectiveness in decreasing the appetite after a few
weeks. If this happens, you should stop taking the medication. Do not take
more than the recommended dose in an attempt to increase its effect.
How should you take Desoxyn?
Follow your doctor's directions carefully. Your doctor will prescribe the
lowest effective dose of Desoxyn; never increase it without approval Do not
take this medication late in the evening; it can cause difficulty sleeping.
--If you miss a dose...
Take it as soon as you remember. If it is almost time for the next dose,
skip the one that you missed and go back to your regular schedule. Never
take 2 doses at the same time.
--Storage instructions...
Store at room temperature.
What side effects may occur when taking Desoxyn?
Side effects cannot be anticipated. If any develop or change in
intensity, inform your doctor as soon as possible. Only your doctor can
determine if it is safe to continue taking Desoxyn.
- Side effects of Desoxyn may include: Changes in sex drive, constipation,
diarrhea, dizziness, dry mouth, exaggerated feeling of well-being,
feeling of unwellness or unhappiness, headache, hives, impaired growth,
impotence, increased blood pressure, overstimulation, rapid or irregular
heartbeat, restlessness, sleeplessness, stomach or intestinal problems,
tremor, unpleasant taste, worsening of tics and Tourette's syndrome
(severe twitching)
Why should this drug not be prescribed?
You should not take Desoxyn if you are also taking a monoamine oxidase
(MAO) inhibitor drug such as Nardil or Parnate. Allow 14 days between
stopping an MAO inhibitor and beginning therapy with Desoxyn.
You should not take Desoxyn if you have glaucoma, advanced hardening of
the arteries, heart disease, moderate to severe high blood pressure, thyroid
problems, or sensitivity to this type of drug. This medication should not be
taken by anyone who suffers from tics (repeated, involuntary twitches) or
Tourette's syndrome or who has a family history of these conditions.
People who are in an agitated state or who have a history of drug abuse
should not take this medication.
Desoxyn should not be used to treat children whose symptoms may be caused
by stress or a psychiatric disorder.
Special warnings about Desoxyn
Desoxyn is not appropriate for all children with symptoms of ADHD. Your
doctor will do a complete history and evaluation before prescribing this
medication. The doctor will take into account the duration and severity of
the symptoms as well as your child's age.
This type of medication can affect the growth of children, so your doctor
will watch your child carefully while he or she is taking this drug. The
long-term effects of this type of medication in children have not been
established.
Desoxyn should be used with caution if you have mild high blood pressure.
Desoxyn may affect your ability to perform potentially hazardous
activities, such as operating machinery or driving a car.
Desoxyn should not be used to combat fatigue or to replace rest.
Possible food and drug interactions when taking Desoxyn
If Desoxyn is taken with certain other drugs, the effects of either could
be increased, decreased, or changed. It is especially important to check
with your doctor before combining Desoxyn with the following:
Antidepressants classified as "tricyclics," such as Elavil, Pamelor, and
Tofranil
Drugs classified as monoamine oxidase (MAO) inhibitors, such as the
antidepressants Nardil and Parnate
Drugs classified as phenothiazines, such as the antipsychotic medications
Compazine and Thorazine
Guanethidine
Insulin
Special information if you are pregnant or breastfeeding
Infants born to women taking this Desoxyn have a risk of prematurity
and low birth weight. Drug dependence may occur in newborns when the mother
has taken this drug prior to delivery. If you are pregnant or plan to become
pregnant, tell your doctor immediately.
Desoxyn makes its way into breast milk. Do not breastfeed while taking
this medication.
Recommended dosage for Desoxyn
ATTENTION DEFICIT HYPERACTIVITY DISORDER
For children 6 years and older, the usual starting dose is 5 milligrams
of Desoxyn taken once or twice a day. Your doctor may increase the dose by 5
milligrams a week until the child responds to the medication. The typical
effective dose is 20 to 25 milligrams a day, usually divided into two doses.
Your doctor may periodically discontinue this drug in order to reassess the
child's condition and see whether therapy is still needed.
Desoxyn should not be given to children under 6 years of age to treat
attention deficit disorder; the safety and effectiveness in this age group
have not been established.
WEIGHT LOSS
For adults and children 12 years and older, the usual starting dose is 5
milligrams taken one-half hour before each meal. Treatment should not
continue for longer than a few weeks. The safety and effectiveness of
Desoxyn for weight loss have not been established in children under age 12.
Overdosage
Any drug taken in excess can have dangerous consequences. If you suspect
an overdose, seek medical attention immediately.
- Symptoms of Desoxyn overdose may include: Abdominal cramps,
agitation, blood pressure changes, confusion, convulsions (may be
followed by coma), depression, diarrhea, exaggerated reflexes, fatigue,
hallucinations, high fever, irregular heartbeat, kidney failure, muscle
aches and weakness, nausea, panic attacks, rapid breathing,
restlessness, shock, tremor, vomiting
Full Desoxyn Prescribing Information
Last updated: 12/2005
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