I have schizoaffective disorder, which is a combination of schizophrenia and bipolar disorder. I also have generalized anxiety disorder (anxiety disorders frequently accompany bipolar disorder). On top of that, I have pre-menstrual dysphoric disorder (PMDD) which is like the pre-menstrual syndrome (PMS) many women experience but worse. Much, much worse. It is especially bad when you already have a disorder like schizophrenia or schizoaffective disorder, a cascade of additional mood swings and depression.