Anxiety and panic can overstimulate the brain, rocket our senses into hyperactivity, and make us feel wired. When we feel keyed-up and on edge, it can feel as though nothing will help. Here we are at risk of jumping right out of our own skin, which would do nothing more than increase both anxiety and panic, and there’s not a thing we can do to settle down. Or is there? It can seem counter-intuitive, but practicing mindfulness when we’re at our most agitated can help when anxiety and panic overstimulate your brain.