Researchers are examining whether a combination of exercise and antidepressant medication can alleviate the symptoms of depression.

Combining regular exercise with taking antidepressant medication may be more effective in treating major depression than medication alone, according to a Feb 2, 2004, news release from the University of Texas Southwestern Medical Center at Dallas. Researchers are conducting a study to determine whether augmenting antidepressant medication treatment with exercise can eliminate all symptoms of depression. Eligible participants are adults ages 18 to 65 who have been treated with selective serotonin reuptake inhibitors (SSRIs) for eight to 12 weeks but who continue to experience symptoms of depression. Participants will complete a supervised 24-week exercise program and will be trained on how to exercise at home.

Exercise is a known stress reliever that can help fight symptoms of depression. Many people who take SSRIs obtain some relief from depression but do not experience full remission. Preliminary results from a pilot study indicate that patients respond favorably to this treatment. The study is funded by a $2.4 million grant from the National Institute for Mental Health.

Source: University of Texas Southwestern Medical Center at Dallas news release

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