General Depression Information

Depression-Effective Treatments are Available

Provides basic information about depression, symptoms, diagnosis, treatment, and where to get help.

The Invisible Disease: Depression

Describes depression as a serious medical illness that can interfere significantly with one's ability to function. Includes symptoms of unipolar major depression and dysthymia, stating that 80 percent of people with depression improve when they receive proper treatment with medication, psychotherapy, or the combination. Highlights recent research findings about depression which will lead to more effective treatments.

Let's Talk about Depression

Designed for teenagers, this document discusses facts about depression, symptoms, treatment, relation to substance abuse, and how to get help.

Questions and Answers about St. John's Wort

There is considerable public interest in claims that extracts from the herb Hypericum perforatum, commonly known as St. John’s wort, may be an effective treatment for depression. Although St. John’s wort is widely prescribed in Europe, no studies of its long-term use have been conducted, and published studies have treated different types of patients and have used several different doses. The NIMH, in collaboration with the NIH Office of Alternative Medicine (OAM) and the NIH Office of Dietary Supplements (ODS), is beginning the first U.S. large-scale controlled clinical trial to assess whether Hypericum has a significant therapeutic effect in patients with clinical depression.

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