articles

Figure 3: Structures deep within the limbic system play a crucial
role in the expression of emotions and the activity of the reward system of
the brain. The experience of pleasure and the modulation of reward is based on
a reward "cascade," a chain of neurons within the limbic system that
interact through various signaling molecules, or neurotransmitters. The
authors propose that a biochemical deficiency in one or more of these neurons
or signaling molecules can supplant an individual's feeling of well being with
anxiety, anger or a craving for a substance that can alleviate the negative
emotions.
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